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What Is Grape Seed Extract, Its Benefits and Side Effects

grape seed extract

Grape seed extract is a dietary supplement available in capsule, tablet, and liquid forms. It’s made from the seeds of grapes and is rich in antioxidants. These substances are known to protect cells, molecules, and organs from damage.

Health Benefits of Grape Seed Extract

Polyphenols, a type of antioxidant, are found in grape seed extract. These chemicals protect cells from damage. They may also help reduce the risk of several chronic diseases, such as heart disease and cancer.

In addition to its antioxidant content, grape seed extract contains other compounds that may offer health benefits. For example, it’s a source of proanthocyanidins, a flavonoid with anti-inflammatory and antimicrobial properties.

Here are more health benefits of grape seed extract:

1. Heart Health

The antioxidants in grape seed extract may help reduce oxidative stress in the body, which can lead to various diseases, including heart disease.

One analysis of multiple studies found that grape seed extract has a beneficial effect on both systolic and diastolic blood pressure. The effect is even more significant with younger and obese participants.

These results are promising, but more research is needed to confirm the effects of grape seed extract on blood pressure.

2. Reduced Inflammation

Grape seed extract may help reduce inflammation throughout your body. This may be beneficial for people with conditions that are characterized by inflammation, such as arthritis and Crohn’s disease.

In one study, people with arthritis took grape seed extract for eight weeks. At the end of the study, they had significantly less pain and stiffness than those who didn’t take the supplement.

Another study examined the effects of grape seed extract in people with Crohn’s disease. After eight weeks, those who took grape seed extract had less inflammation and fewer symptoms than those who didn’t take the supplement.

3. Cancer Prevention

Grape seed extract may also help prevent cancer. This is because it’s rich in antioxidants and has anti-inflammatory properties.

One test-tube study found that grape seed extract was able to kill breast cancer cells. Another test-tube study found that grape seed extract was able to stop the growth of colon cancer cells.

The Side Effects of Grape Seed Extract

Grape seed extract is generally safe to take. However, it can cause some side effects. Here is a list of potential adverse effects of grape seed extract:

  • Dizziness
  • Upset stomach
  • Diarrhea
  • Dry mouth
  • Muscle cramps

Grape seed extract can also interact with certain medications. For example, it can increase the risk of bleeding when taken with blood thinners. Therefore, speaking to a doctor before taking grape seed extract is important, especially if you’re on any medications.

Recommended Dosage

The recommended dose of this medication varies depending on various factors such as gender, age, weight, and medical history. In general, doses ranging from 100 mg to 400 mg daily for six to 12 weeks have been used in studies.

More importantly, check with your healthcare provider before taking grape seed extract. This is especially important if you have a medical condition or are taking any medications, as grape seed extract can interact with some drugs. 


Grape seed extract is a popular supplement that is claimed to have a range of health benefits. These include improving heart health, reducing inflammation, and helping to prevent cancer.

Grape seed extract is generally safe to take, but it can interact with certain medications. If you’re considering taking grape seed extract, talk to your doctor first to ensure it’s right for you.

MTC Industries is the best place to go for high-quality bulk finished products. We distribute innovative and commodity ingredients for use in nutritional supplements like grape seed extract, food and beverage products, cosmetics, and pharmaceuticals. Request a sample today!

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